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Pharmaceutical Intermediates 1

1. Atorvastatin Series
ATS-5: (R) Ethy l -4-cyano-3-hydroxybutanoate
ATS-8: (4R, 6R) -t-Buty l -6-cyanomethy l - 2, 2-dimethy l -1, 3-dioxane-4-acetate
ATS-9: (4R, Cis) -1, 1-dimethy l ethy l -6-aminoethy l -2, 2-dimethy l -1, 3-dioxane-4-acetate
M4: 4-Fluoro -α- (2-methy l -1-oxopropy l) - -oxo- N, ß -dipheny l benzene butaneamide
L1: (4R, Cis) -1, 1 -dimethy l ehty l -6- [ 2- [ 4-fluoropheny l ] -5- (1 -i sopropy l) -3- pheny l -4- [ (pheny l amino) carbony ] -1H-pyrrol-1-y l ] ethy l ] -2, 2-dimethy l -1, 3-dioxane-4-acetate
3-Ethy l -5- (2 - hydroxyethy l) -4-methy l thiazio l ium bromide
2,2 -Dimethoxy propane
iso-butyry l methy l acetate
Diethy l methoxyborane
Lithium d i i sopropy l amide

2. Fluvastatin Series
Q-1: (E) -3- [ 3' - (4' ' -fluoropheny) -1' -(1' ' -methy l ehty l) -1H-indo l - 2' ' -y l ] -2-propena l
Q-2: t-Buty l (E) -7- (3' -(4' ' -fluoropheny l) -1' -methy l ethy l - indo l -2' - y l) 3-hydroxy-5-oxo-6-heptenoate
Q-3: t-Buty l (E) -3, 5-dihydroxy-7- (3' - (4' ' -fluoropheny l) -1' -methy l ethy l - indo l -2' - y l) -6-heptenoate

3. Rosuvastatin Series
D-5: (4R-Cis)-6- ( (acety l oxy) methy l) -2, 2-dimethy l-1, 3-dioxane-4-acetic acid, 1, 1-dimethy l ethy l ester
D-6: (4R-Cis)-6-hydroxymethy l -2, 2-dimethy l -1, 3-dioxane-4- aceti acid, 1, 1-dimethy l ethy l ester
Z-6: 4- (4-Fluoropheny l) -6-isopropy l-2- ( (N-methy l-N-methy l sulfony l) amino) pyrimidine-5-carboxylate
Z-7: 4- (4-Fluoropheny l) -6-isopropy l-2- ( (N-methy l-N-methy l sulfony l) amino) pyrimidine-5-y l-methanol
R1: tert-buty l (E) - (6 {2- [ 4-(4-fluoropheny l) -6-isopropy l -2- [ methy l (methy l su l fony l) amino ] pyrimidin -5-y l ] viny l} - (4R, 6S) -2-dimethy l [ 1, 3] dioxan -4-y l ) acetate
R-1.5: (+) - (3R, 5S), tert-buty l 7-[ 4- (4-fluoropheny l) -6-isopropy l-2- (N-methy l-N-methy l sulphony l amino) -pyrimidin-5-yl ]-3, 5-dihydroxy-6 (E) -heptenate
J-6: Methy l (3R) -3-(tert-buty l dimethy l silyloxy) -5-oxo-6-tripheny l phosphorany l idene hexanoate

4. Doxazosin series
4-Amino-2-chloro-6, 7-dimethoxy quinazoline
N- (1,4-benzodioxan-2-y l carbony l) piperazine HC l

5. Methyl 3-oxo valerate

6. 3-Hexyn-2-ol

7. D.D.Q 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone

8. 3-Aminophrazine-2-carboxylic acid
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